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0 0.5 1 1.5 2+ Hospitalization 70% Improvement Relative Risk Recovery time 33% c19mp.com Hetero et al. Molnupiravir for COVID-19 RCT EARLY Favors molnupiravir Favors control
Hetero, 741 patient molnupiravir early treatment RCT: 70% lower hospitalization [p=0.003] and 33% faster recovery [p=0.0001] https://c19p.org/hetero
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Hetero Announces Interim Clinical Results from Phase III Clinical Trials of Molnupiravir conducted in India
Hetero Press Release
9 Jul 2021    Source   PDF   Share   Tweet
Interim results for CTRI/2021/05/033739, showing lower mortality and faster recovery.
Concerns have been raised that the mutagenic mechanism of action may create dangerous variants or cause cancer [Hadj Hassine, Swanstrom].
risk of hospitalization, 69.6% lower, RR 0.30, p = 0.003, treatment 7 of 371 (1.9%), control 23 of 370 (6.2%), NNT 23.
recovery time, 33.3% lower, relative time 0.67, p < 0.001, treatment 371, control 370.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Hetero et al., 7/9/2021, Randomized Controlled Trial, India, South Asia, peer-reviewed, 1 author.
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